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Eco-toxicological Testing of Chemicals

Guangdong Detection Center of Microbiology (GDDCM), under the approval of the authoritative department, was established on the basis of Guangdong Institute of Microbiology and awarded the provincial China Metrology Accreditation (CMA) certificate in 1999. In the year 2004, it was accredited by China National Accreditation of Laboratory (CNAL). GDDCM provides testing data and analysis reports for trade license, product quality evaluation, which are recognized and accepted internationally. Special qualifications include:

·Recognized laboratory of Principles of good laboratory practice (GLP) by Certification and Accreditation Administration of the People's Republic of China.

·Recommended Good Laboratory Practices Testing Laboratory for Chemical by Ministry of Environmental Protection.

·Approved Environmental Testing Institution for pesticides registration by the Ministry of Agriculture.

·Allied Secretariat of Subcommittee 1 on Chemicals Toxicity Inspection of National Technical Committee 251 on Dangerous Chemicals Management of Standardization Administration of China (SAC/TC251/SC1).

GDDCM has carried out as following chemical services testing in accordance with the OECD GUIDELINE FOR THE TESTING OF CHEMICALS:

u Section 1 Physical-Chemical properties

¨ Test No. 105: Water Solubility

¨ Test No. 106: Adsorption -- Desorption Using a Batch Equilibrium Method

¨ Test No. 107: Partition Coefficient (n-octanol/water): Shake Flask Method

¨ Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method

¨ Test No. 111: Hydrolysis as a Function of pH

¨ Test No. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)

u Section 2 Effects on Biotic Systems

¨ Test No. 201: Freshwater Alga and Cyanobacteria, Growth Inhibition Test

¨ Test No. 202: Daphnia sp. Acute Immobilisation Test

¨ Test No. 203: Fish, Acute Toxicity Test

¨ Test No. 204: Fish, Prolonged Toxicity Test: 14-Day Study

¨ Test No. 207: Earthworm, Acute Toxicity Tests

¨ Test No. 208: Terrestrial Plant Test: Seedling Emergence and Seedling Growth Test

¨ Test No. 209: Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation)

¨ Test No. 210: Fish, Early-Life Stage Toxicity Test

¨ Test No. 211: Daphnia magna Reproduction Test

¨ Test No. 212: Fish, Short-term Toxicity Test on Embryo and Sac-Fry Stages

¨ Test No. 215: Fish, Juvenile Growth Test

¨ Test No. 216: Soil Microorganisms: Nitrogen Transformation Test

¨ Test No. 217: Soil Microorganisms: Carbon Transformation Test

¨ Test No. 227: Terrestrial Plant Test: Vegetative Vigour Test

¨ Test No. 299: Seed Germination/Root Elongation Toxicity Test

u Section 3 Degradation and Accumulation

¨ Test No. 301: Ready Biodegradability

u 301A DOC Die-Away Test

u 301B CO2 Evolution Test

u 301C Modified MITI Test Ⅰ

u 301D Closed Bottle Test

u 301F Manomettric Respiremetry Test

¨ Test No. 302B: Inherent Biodegradability: Zahn-Wellens/ EVPA Test

¨ Test No. 302C: Inherent Biodegradability: Modified MITI Test (II)

¨ Test No. 305: Bioaccumulation in Fish: Aqueous and Dietary Exposure

¨ Test No. 305B: Bioconcentration: Semi-Static Fish Test

¨ Test No. 306: Biodegradability in Seawater

¨ Test No. 310: Ready Biodegradability - CO2 in sealed vessels (Headspace Test)

u Section 4 Health Effects

¨ Test No. 471: Bacterial Reverse Mutation Test

u Annex Qualification Certificate

¨ GLP Compliance Statement, Certification and Accreditation Administration

¨ Chemical Testing Good Laboratory Practices, Ministry of Environmental Protection

¨ Recommended Laboratory for Environmental Toxicology tests for pesticide registration, Ministry of Agriculture